Mucomyst Contrast Prophylaxis ProtocolThe following is the standard Mucomyst prophylaxis protocol used in some patients with chronic renal insufficiency and in whom an intra-venous or intra-arterial contrast exam is required. The referring physician, who may wish to consult with an RMG physician, must prescribe Mucomyst. After the contrast exam is complete, the patient should be hydrated (oral or intravenous) and should have renal function follow-up by the referring physician.
The pre-treatment protocol (Reference: NEJM 2000; 343: 180-184) is as follows:
Mucomyst (Acetylcysteine) solution 600 mg orally twice a day for four (4) doses beginning the day before the contrast exam.
Mucomyst (Acetylcysteine) solution comes in 10% (100mg/ml) and 20% (200mg/ml) concentrations in 4, 15, or 30 ml vials. Most pharmacists dispense the doses in individual dose syringes and have patients squirt each dose into a glass of soda.
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